DTUS1710

Dr. Joel Berg Dr. L. Stephen Buchanan Dr. Arnaldo Castellucci Dr. Gorden Christensen Dr. Rella Christensen Dr. William Dickerson Hugh Doherty Dr. James Doundoulakis Dr. David Garber Dr. Fay Goldstep Dr. Howard Glazer Dr. Harold Heymann Dr. Karl Leinfelder Dr. Roger Levin Dr. Carl E. Misch Dr. Dan Nathanson Dr. Chester Redhead Dr. Irwin Smigel Dr. Jon Suzuki Dr. Dennis Tartakow Dr. Dan Ward Editorial Board DENTAL TRIBUNE The World’s Dental Newspaper · US Edition of humor, dental professionals and scientists explain how bacteria multi- ply and collect in the mouth to form a thick layer called plaque biofilm, which is more harmful than free-flow- ing bacteria and may increase the potential for bad breath and gingivitis. The video also depicts when LISTER- INE Antiseptic was first formulated in 1879 and offers rare glimpses of retro advertisements. “Plaque is not a simple matter, and there is more to be concerned about than meets the eye,” said Marcelo Araujo, DDS, PhD, associate director, scientific & professional affairs, John- son & Johnson Consumer & Personal Products Worldwide, division of John- son & Johnson Consumer Companies. “We all need to understand the effects of the plaque biofilm. This ‘docummercial’ will educate view- ers on the important role that rinsing plays in fighting the plaque biofilm. “We are very grateful that the mak- ers of LISTERINE share our commit- ment to children’s oral health and chose to direct proceeds from the pro- duction of ‘This Is Your Mouth’ to NCOHF smile-saving programs,” said Fern Ingber, NCOHF president and CEO. “This generous donation will enable NCOHF affiliates to continue providing quality treatment and criti- cal preventive services to children from vulnerable populations to effec- tively break the cycle of preventable pediatric dental disease.” The video may be viewed at www.listerine.com/ yourmouth. DT percent, but if oral cancer is detect- ed early, that rate rises to 90 per- cent. McDevitt and his team are work- ing to create an inexpensive chip that can differentiate premalignan- cies from the 95 percent of lesions that will not become cancerous. The minimally invasive tech- nique would deliver results in 15 minutes instead of several days, as lab-based diagnostics do now. Instead of an invasive, painful biop- sy, the new procedure requires just a light brush of the lesion on the cheek or tongue with an instrument that looks like a toothbrush. “This area of diagnostics and testing has been terribly challeng- ing for the scientific and clinical community,” said McDevitt, who came to Rice from the University of Texas at Austin in 2009. “Part of the problem is that there are no good tools currently available that work in a reliable way.” He said patients with suspi- cious lesions, which are usually discovered by dentists or oral sur- geons, end up getting scalpel or punch biopsies as often as every six months. “People trained in this area don’t have any trouble finding lesions,” McDevitt said. “The issue is the next step — tak- ing a chunk of someone’s cheek. The heart of this paper is develop- ing a more humane and less painful way to do that diagnosis, and our technique has shown remarkable success in early trials.” Nano-bio-chips are small, semi- conductor-based devices that com- bine the ability to capture, stain and analyze biomarkers for a variety of health woes that also include car- diac disease, HIV and trauma inju- ries. Researchers hope the eventual deployment of nano-bio-chips will dramatically cut the cost of medical diagnostics and contribute signifi- cantly to the task of bringing quality health care to the world. The new study compared results of traditional diagnostic tests to those obtained with nano-bio-chips on a small sample of 52 partici- pants. All of the patients had visible oral lesions of leukoplakia or eryth- roplakia and had been referred to specialists for surgical biopsies or removal of the lesions. The chips should also be able to see when an abnormality turns precancerous. “You want to catch it early on, as it’s transforming from pre-cancer to the earliest stages of cancer, and get it in stage one. Then the five-year survival rate is very high,” he said. “Currently, most of the time, it’s captured in stage three, when the survivability is very low.” The device is on the verge of entering a more extensive trial that will involve 500 patients in Hous- tions will be made to the National Children’s Oral Health Foundation, a very worthwhile organization. Chil- dren across the country need to spend more time on the playground and less time with a toothache.” In the video, which blends pop culture with science and a good dose News DENTAL TRIBUNE | July 20102A Publisher & Chairman Torsten Oemus t.oemus@dental-tribune.com Vice President Global Sales Peter Witteczek p.witteczek@dental-tribune.com Chief Operating Officer Eric Seid e.seid@dental-tribune.com Group Editor & Designer Robin Goodman r.goodman@dental-tribune.com Editor in Chief Dental Tribune Dr. David L. Hoexter d.hoexter@dental-tribune.com Managing Editor/Designer Implant, Endo & Lab Tribune Sierra Rendon s.rendon@dental-tribune.com Managing Editor/Designer Ortho Tribune & Show Dailies Kristine Colker k.colker@dental-tribune.com Online Editor Fred Michmershuizen f.michmershuizen@dental-tribune.com Account Manager Mark Eisen m.eisen@dental-tribune.com Marketing Manager Anna Wlodarczyk a.wlodarczyk@dental-tribune.com Sales & Marketing Assistant Lorrie Young l.young@dental-tribune.com C.E. Manager Julia E. Wehkamp j.wehkamp@dental-tribune.com Dental Tribune America, LLC 213 West 35th Street, Suite 801 New York, NY 10001 Tel.: (212) 244-7181 Fax: (212) 244-7185 Published by Dental Tribune America © 2010 Dental Tribune America, LLC All rights reserved. Dental Tribune strives to maintain the utmost accuracy in its news and clini- cal reports. If you find a factual error or content that requires clarification, please contact Group Editor Robin Goodman at r.goodman@dental-tribune.com. Dental Tribune cannot assume respon- sibility for the validity of product claims or for typographical errors. The pub- lisher also does not assume responsibility for product names or statements made by advertisers. Opinions expressed by authors are their own and may not reflect those of Dental Tribune America. Do you have general comments or criticism you would like to share? Is there a particular topic you would like to see more articles about? Let us know by e-mailing us at feedback@dental-tribune.com. If you would like to make any change to your subscription (name, address or to opt out) please send us an e-mail at database@dental-tribune.com and be sure to include which publication you are referring to. Also, please note that subscription changes can take up to 6 weeks to process. Tell us what you think! f DT page 1A, NCOHF f DT page 1A, Chip ton, San Antonio and England. That could lead to an application for FDA approval in two to four years. Eventually, McDevitt said, den- tists may be the first line of defense against oral cancers, with the abili- ty to catch early signs of the disease right there in the chair. McDevitt’s co-authors include Rice senior research scientist Pierre Floriano, Rice postdoctoral associ- ate Shannon Weigum and Spencer Redding, a professor and chair of the Department of Dental Diag- nostic Science at theUTHSC at San Antonio. Also contributing were: UTHSC San Antonio’s Chih-Ko Yeh, Ste- phen Westbrook and Alan Lin, all of the Department of Dental Diag- nostic Science; H. Stan McGuff of the Department of Pathology; and Frank Miller, Fred Villarreal and Stephanie Rowan, all of the Department of Otolaryngology, Head and Neck Surgery; UTHSC Houston’s Nadarajah Vigneswaran of the Department of Diagnostic Science; and Michelle Williams of the Department of Pathology at the University of Texas M.D. Anderson Cancer Center. The researchers received a Grand Opportunity Grant from the National Institute for Dental and Craniofacial Research Division of the National Institutes of Health for the work. DT that brushing and flossing alone isn’t enough to keep germs at bay,” said Harris, in a press release announcing the new video. “I’m excited that by viewing this documentary on the website, dona- (Photo/www.listerine.com/yourmouth)