IM0310

14 I I research _ dental implant loading Tab. 2_Summarized data from the studies /approaches used in this review with reference to early loading. Tab. 3_Summarized data from the studies/approaches used in this review with reference to delayed loading. implants3_2010 The findings from this clinical study showed that the placement of SLA transmucosal implants in the mandibular area and their immediate loading with 3-unit fixed partial dentures may be a safe and successful procedure.19 Gioacchino Cannizzaro, MicheleLeone,MarcoEspositohaveperformedaone year follow-up of a single cohort study. Thirty three consecutively treated edentulous patients received 202implantsinthemaxila.In10patients,53implants wereimmediatelyinsertedinfreshextractionsockets. Threeimplantsintwopatientsdidnotreachsufficient stability and were left to heal for 45 to 90 days. All restorations (21 fixed prostheses and 12 overden- tures) were delivered the same day of the surgery. No major complication occurred. Five patients experi- encedbiologiccomplication,e.g.peri-implantitis;ten experienced prosthetic complication. Two implants failed in two patients but were successfully replaced the same day they were removed. No prosthesis failed.Implantsplacedintheedentulousmaxillawith a flapless procedure can be successfully loaded the same day of surgery.20 The activity around dental im- plants has been approached by Hiroto Sasaki et al. who performed a study to determine dynamic changesinbonemetabolismaroundosseointegrated titanium implants under mechanical stress. After in- sertionofimplants,theuptakeratioincreasedduring the first week and then decreased gradually. It was significantly higher than baseline on days 4.7 and 10 (p < 0.01 Friedman test) and during the second and thirdweek(p<0.5Steeltest).However,itwasnotsig- nificantly higher at 4 weeks and 7 weeks (i.e. meta- bolic activity had returned to the baseline level). The uptake ratio changed with the loading. With 2.0 and 4.0-N loading, change of activities over the 7 week experimental period was almost the same in terms of magnitude and timing.The ratio reached a maxi- mum during the first week (more than twice that without loading) and then decreased a little. Meta- bolic activity returned to the baseline level at about 2 to 7 weeks after loading. The ratio from 3 days to 6 weeks after loading was significantly higher than without loading (Friedman and Steel test, P < 0.05). There was no significant difference 7 weeks after loading. The results for the 0.5 and 1.0-N loading groups were similar but different from those for the 2.0 and 4.0-N loading groups. With the smaller loadings, the uptake ratio gradually increased after loading and returned to the baseline level at 7 days. It then decreased, reaching baseline level at 2 to 7 Load time Splint time Sit. Impl. type Follow up No.of pac. No.of impl. Succ. rate Reference Lev.of evid Early loading 2 Months Ed. max. Ed. mandib. Osseotite 60 Months 142 pac. 526 impl. 97.9 % Sullivan et al. B Early loading 1-11 Days Ed. post. mandib. Ed. post. max. ITI Straumann 12 Months 40 pac. 82 impl. 98.8 % Giuseppe Luongo et al. B Early loading 7 Days Ed. mandib. Novum Brånemark 12 Months 10 pac. 20 impl. 90 % Els De Smet et al. B Load time Splint time Sit. Impl. type Follow up No.of pac.no.of impl. Succ. rate Reference Lev.of evid Delayed loading 4 Months Ed. mandib. Novum Brånemark 1 Year Half 2 Years 10 pac. 20 impl. 90 % Els De Smet et al. C Delayed loading 3 Months Max. esthetic zone Sweden & Martina 24 Months 20 pac. 20 impl. 100 % Roberto Crespi et al. B Delayed loading 4 Months Part. Edent. Zimmer Swiss Plus 36 Months 20 pac. 56 impl. 100 % Gioacchino Cannizzaro et al. B