Dental Tribune United Kingdom Edition

techniques to the visualisation & characterisation of the tooth structure and how treatments work in-vitro. This work was carried out in conjunction with UK uni- versities Cambridge, Leeds and Manchester, and uses various methods including , Scanning Transmission Electron Micro- scopy (STEM), Environmental Scanning Electron Microsco- py (ESEM) and Focussed Ion Beam Scanning Electron Mi- croscopy (FIB SEM). The research shows the transformation of Novamin in saliva - changes are not only seen in structure but can also be measured in changes in chemical compositition. This dynamic reparative layer is harder than natural dentine15,16 ; it is able to withstand daily oral challenges such as tooth brush abrasion, and dietary acid challenges.9,13,16,17 With regular twice daily use,16,18,19 it helps maintain lasting protection to deliver clinically proven relief from the pain of dentine hyper- sensitivity.18,19,20 GlaxoSmithKline-Dentsply Collaboration GlaxoSmithKline are work- ing with DENTSPLY, a global leader in professional dental products, to develop the new Sensodyne NUPRO Profes- sional Range also utilising No- vaMin® technology. The in–Of- fice Prophy Paste is the only prophylaxis product containing the unique patented ingredient, NovaMin®. Dr Teresa Layer Vice President, Oral Healthcare R&D is hugely excited about- forging a relationship with Dentsply to work on taking the brand forward. 50 years of Sensodyne Expertise Sensodyne’s strengths lie in its dental and clinical heritage, GlaxoSmithKline acknowl- edges it owes a lot to all those who have worked on Senso- dyne in the last 50 years both internally and externally. “The next 50 years will be even more exciting for GSK Sensodyne with continued investment into leadership in oral care through science. We are liv- ing in exponential times” Ter- esa Layer, Vice President, Oral Healthcare R&D. DT ‘The next 50 years will be even more excit- ing for GSK Sensodyne ’ Visual representation of dentine cross- section and dynamic reparative layer March 14-20, 2011United Kingdom Edition FenderMate® is a trademark registered by Directa AB. Registered Design and Patent pending. Mimics natural contour Flexible wing exerts pressure for maintained separation and cervical adaption Inserts like a wedge Compressing wedge mimics natural separation and prevents overhangs World’s Fastest Composite Matrix? 3216-1009©DirectaAB Matrix Distributed in the UK by Trycare, Tel. 01274-88 10 44 More Designs by Dentists www.directadental.com page 15DTß Professor J.M. (‘bob’) ten Cate References 1. Professor Francis Hughes, Periodontology, Kings College London Dental Institute- “ Past, Present and Future: Towards periodontal Health for all.” 2. Professor J.M (‘bob’) ten Cate, Head of Preventive Dentistry at the academic Center for Dentistry Amsterdam (ACTA)- “Past, Present and Future: Toothpastes in Caries prevention”, 3. Professor David Bartlett, Head of Prosthodontics, King’s College London Dental Institute-“ Past, Present and Future: Erosive Tooth wear” 4. Professor Martin Addy, Division of Restorative Dentistry (Periodontol- ogy) University of Bristol-“ Past, Present and Future: Dentine Hypersensitivity” 5. GSK data on file. Ipsos Healthcare Professional Mouth Care full year 2010. 6. United States Patent No. 5,735,942; Title: Compositions Containing Bioactive Glass and Their Use in Treating Tooth Hypersensitivity, issued April 7, 1998 7. David C. Greenspan NovaMin® and Tooth Sensitivity—An Overview (J Clin Dent 2010;21[Spec Iss]:61–65) 8. Greenspan DC, Burwell A, Jennings D, Muscle D. NovaMin®and Dentine Hypersensitivity – In Vitro Evidence of Efficacy. Journal of Clinical Dentistry Special Issue, Nov 2010. 9. LaTorre G,Greenspan DC. Role of ionic release from NovaMin® (calcium sodium phosphosilicate) in tubule occlusion: In-vitro analyses. Journal of Clinical Dentistry, Special Issue, Nov 2010 10. Efflant S E, Magne P, Douglas W H, Francis L F. Interaction between bioactive glasses and human dentin,. J Mater Sci.Mater Med, 26[6]:557-565 (2002) 11. Clark AN E, LaTorre G, McKenzie K Dentin Surface Morphological and Chemical Changes Produced by Treatment with a Bioactive Prophylax- is Agent. J Dent Res 81 (Spec Iss A): 2182. 2002 12. GSK Data held on file (2010) 13. Zhong JP et al. The kinetics of bioactive ceramics Part VII: Binding of collagen to hydroxyapatite and bioactive glass, Zhong J P, LaTorre G P, Hench L L, in Bioceramics 7 Ed O H Andersson and A Yli-Urpo. Proceedings of the 7th International Symposium on Ceramics in Medicine, Turku, Finland, July 1994 14. Burwell AK and Greenspan DC. Quantitative Tubule Occlusion in an In Vitro Remineralization/ Demineralization Model. J Dent Res 85 (Spec Iss C):0568 (PEF), 2006. 15. GSK Data held on File (2010) 16. Zhejun Wang, Yue Sa, Salvatore Sauro, Hao Chen , Wenzhong Xinga, Xiao Ma, Tao Jiang, Yining Wang, Effect of desensitising toothpastes on dentinal tubule occlusion: A dentine permeability measurement and SEM in vitro study Journal of Dentistry 38 ( 2 0 1 0 ) 4 0 0 – 4 1 0 17. Pradeep AR, Sharma A, Comparison of the Clinical Efficacy of a dentifrice containing Calcium Sodium Phosphosilicate with a Dentifrice containing potassium nitrate and a placebo on dentinal hypersensitivity: A randomized clinical trial. J Periodontal. Aug;81(8):1167-73 (2010) 18. Salian S, Thakar Kulkarni S, LaTorre G. A Randomized, Control- led, Clinical Study Evaluating the Efficacy of Two Desensitizing Dentifrices. J Clin Dent. Special Issue, accepted for Publication (2010) 19. Du M Q, Bian Z, Jiang H, Greenspan DC, Burwell AK, Zhong J, Tai BJ, Clinical evaluation of a dentifrice containing calcium sodium phosphosilicate (NovaMin) for the treatment of dentin hypersensitivity. Am J Dent. 21(4); 210-214 (2008)